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Difino
| • | Tissue engineering can perhaps be best defined as the use of a combination of cells, engineering materials, and suitable biochemical factors to improve or replace biological functions in an effort to effect the advancement of medicine. Probably the first definition of tissue engineering was by Langer and Vacanti who stated it to be "an interdisciplinary field that applies the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain, or improve tissue functionࢀ-2322; MacArthur and Oreffo (as cited in "References") defined tissue engineering as "understanding the principles of tissue growth, and applying this to produce functional replacement tissue for clinical use." A further description goes on to say that an "underlying supposition of tissue engineering is that the employment of natural biology of the system will allow for greater success in developing therapeutic strategies aimed at the replacement, repair, maintenance, and/or enhancement of tissue function." These more general definitions are driven in part by recent scientific progress with completely autologous approaches. That is, many groups (Nicolas L'Heureux at Cytograft Tissue Engineering, Julie Campbell at University of Queensland etc, Loex laboratories at the Universite of Laval etc.) are demonstrating functional tissue engineered devices/organs without using synthetic biomaterials/scaffolds. These recent approaches are clearly based more on an understanding of cell biology than materials science. In 2003, the NSF published a report titled Field", which gives a thorough description of the history of this field. A typical tissue engineering solution consists of a number of parts as alluded to above. This article will discuss each part in turn, along with its implications. Source: [wikipedia: tissue engineering]
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biomedical_engineering:technology
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Dentigenix Inc. |
| | dentin regeneration products in development; tissue engineering for dentistry and craniofacial restoration.
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diaDexus |
| | dedicated to the discovery and commercialization of novel molecular diagnostics. a joint venture between smithkline beecham and incyte.
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Genzyme Biosurgery - Biotherapeutic and Biomaterial Products |
| | biotherapeutic and biomaterial products designed to improve the health of patients in the orthopaedics and post-surgical adhesive disease areas.
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Georgia Tech/Emory Center for the Engineering of Living Tissues |
| | a research center for technology development, includes center specific information and a newsletter.
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Isotis |
| | isotis, a dutch biomedical company with a focus on orthopaedics, merged with modex, a swiss biotechnology company with a focus on wound management.
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Macropore Biosurgery, Inc. |
| | specializing in the use of adipose tissue as a source of regenerative cells and bioresorbable mechanical support. includes glossary, faq, products and services offered from san diego, california.
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MatTek Corporation |
| | company involved in tissue engineering of human cell-based tissue engineering constructs.
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Pittsburgh Tissue Engineering Initiative |
| | regional biomedical collaboration for economic development through the advancement and commercialization of tissue engineering and related technologies.
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Regeneration Technologies, Inc. (RTI) |
| | company involved in processing human tissue for allogenic grafts used in orthopedic, oral maxillofacial, urinary and cardiovascular surgeries.
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The Liver Group |
| | a registered charity which administers the liver for life appeal. they aim to develop an artificial liver.
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Tissue Engineering |
| | non-commercial resources combining recent news, publications, and general information.
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Tissue engineering and cell culture tools |
| | chambers for maintaining differentiated tissues in culture.
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Tissue Engineering Pages |
| | tissue engineering portal, with membership features. artificial organs, cell culture, biomaterials, transplantation, news, jobs.
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Tissue Engineering Research and Development Center |
| | research and education in bone and cartilage tissue engineering, plus cardiac muscle, pancreatic islets, and urinary bladder, and stem cell replacement.
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Tissue Engineering Society International |
| | sponsors journal tissue engineering. international association of persons engaged or interested in the field of tissue engineering.
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Tissue Regenerating Therapeutics - Stem Cells |
| | stem cell links and general information.
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TissueGene, Inc |
| | tissue engineering for the regenerative orthopedic therapeutics.
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UK Centre for Tissue Engineering |
| | a multi-disciplinary research collaboration between the university of manchester and the university of liverpool. includes news, research, and a list of industrial partners.
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